HTLV-1 Integration into Transcriptionally Active Genomic Regions Is Associated with Proviral Expression and with HAM/TSP

Human T-lymphotropic virus type 1 (HTLV-1) causes leukaemia or chronic inflammatory disease in ∼5% of infected hosts. The level of proviral expression of HTLV-1 differs significantly among infected people, even at the same proviral load (proportion of infected mononuclear cells in the circulation)....

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Detalles Bibliográficos
Autores principales: Meekings, Kiran N., Leipzig, Jeremy, Bushman, Frederic D., Taylor, Graham P., Bangham, Charles R. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265437/
https://www.ncbi.nlm.nih.gov/pubmed/18369476
http://dx.doi.org/10.1371/journal.ppat.1000027

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