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RNAi Screen Reveals an Abl Kinase-Dependent Host Cell Pathway Involved in Pseudomonas aeruginosa Internalization
Internalization of the pathogenic bacterium Pseudomonas aeruginosa by non-phagocytic cells is promoted by rearrangements of the actin cytoskeleton, but the host pathways usurped by this bacterium are not clearly understood. We used RNAi-mediated gene inactivation of ∼80 genes known to regulate the a...
Autores principales: | Pielage, Julia F., Powell, Kimberly R., Kalman, Daniel, Engel, Joanne N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265438/ https://www.ncbi.nlm.nih.gov/pubmed/18369477 http://dx.doi.org/10.1371/journal.ppat.1000031 |
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