Improved Protective Efficacy of a Species-Specific DNA Vaccine Encoding Mycolyl-Transferase Ag85A from Mycobacterium ulcerans by Homologous Protein Boosting

Vaccination with plasmid DNA encoding Ag85A from M. bovis BCG can partially protect C57BL/6 mice against a subsequent footpad challenge with M. ulcerans. Unfortunately, this cross-reactive protection is insufficient to completely control the infection. Although genes encoding Ag85A from M. bovis BCG...

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Detalles Bibliográficos
Autores principales: Tanghe, Audrey, Dangy, Jean-Pierre, Pluschke, Gerd, Huygen, Kris
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265439/
https://www.ncbi.nlm.nih.gov/pubmed/18350112
http://dx.doi.org/10.1371/journal.pntd.0000199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265439/
https://www.ncbi.nlm.nih.gov/pubmed/18350112
http://dx.doi.org/10.1371/journal.pntd.0000199

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