Identification of Small Molecule Inhibitors of Pseudomonas aeruginosa Exoenzyme S Using a Yeast Phenotypic Screen

Pseudomonas aeruginosa is an opportunistic human pathogen that is a key factor in the mortality of cystic fibrosis patients, and infection represents an increased threat for human health worldwide. Because resistance of Pseudomonas aeruginosa to antibiotics is increasing, new inhibitors of pharmacol...

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Detalles Bibliográficos
Autores principales: Arnoldo, Anthony, Curak, Jasna, Kittanakom, Saranya, Chevelev, Igor, Lee, Vincent T., Sahebol-Amri, Mehdi, Koscik, Becky, Ljuma, Lana, Roy, Peter J., Bedalov, Antonio, Giaever, Guri, Nislow, Corey, Merrill, Rod A., Lory, Stephen, Stagljar, Igor
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265467/
https://www.ncbi.nlm.nih.gov/pubmed/18454192
http://dx.doi.org/10.1371/journal.pgen.1000005

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