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From Classical Genetics to Quantitative Genetics to Systems Biology: Modeling Epistasis
Gene expression data has been used in lieu of phenotype in both classical and quantitative genetic settings. These two disciplines have separate approaches to measuring and interpreting epistasis, which is the interaction between alleles at different loci. We propose a framework for estimating and i...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265472/ https://www.ncbi.nlm.nih.gov/pubmed/18369448 http://dx.doi.org/10.1371/journal.pgen.1000029 |