Genome-Wide Assessments Reveal Extremely High Levels of Polymorphism of Two Active Families of Mouse Endogenous Retroviral Elements

Endogenous retroviral elements (ERVs) in mice are significant genomic mutagens, causing ∼10% of all reported spontaneous germ line mutations in laboratory strains. The majority of these mutations are due to insertions of two high copy ERV families, the IAP and ETn/MusD elements. This significant lev...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Maksakova, Irina A., Gagnier, Liane, van de Lagemaat, Louie N., Mager, Dixie L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265474/
https://www.ncbi.nlm.nih.gov/pubmed/18454193
http://dx.doi.org/10.1371/journal.pgen.1000007

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