Intrinsically Disordered Proteins Display No Preference for Chaperone Binding In Vivo

Intrinsically disordered/unstructured proteins (IDPs) are extremely sensitive to proteolysis in vitro, but show no enhanced degradation rates in vivo. Their existence and functioning may be explained if IDPs are preferentially associated with chaperones in the cell, which may offer protection agains...

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Detalles Bibliográficos
Autores principales: Hegyi, Hedi, Tompa, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265518/
https://www.ncbi.nlm.nih.gov/pubmed/18369417
http://dx.doi.org/10.1371/journal.pcbi.1000017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265518/
https://www.ncbi.nlm.nih.gov/pubmed/18369417
http://dx.doi.org/10.1371/journal.pcbi.1000017

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