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GADD45A Does Not Promote DNA Demethylation
Although DNA methylation patterns in somatic cells are thought to be relatively stable, they undergo dramatic changes during embryonic development, gametogenesis, and during malignant transformation. The enzymology of DNA methyltransferases is well understood, but the mechanism that removes methylat...
Autores principales: | Jin, Seung-Gi, Guo, Cai, Pfeifer, Gerd P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265528/ https://www.ncbi.nlm.nih.gov/pubmed/18369439 http://dx.doi.org/10.1371/journal.pgen.1000013 |
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