Uncovering a Macrophage Transcriptional Program by Integrating Evidence from Motif Scanning and Expression Dynamics

Macrophages are versatile immune cells that can detect a variety of pathogen-associated molecular patterns through their Toll-like receptors (TLRs). In response to microbial challenge, the TLR-stimulated macrophage undergoes an activation program controlled by a dynamically inducible transcriptional...

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Detalles Bibliográficos
Autores principales: Ramsey, Stephen A., Klemm, Sandy L., Zak, Daniel E., Kennedy, Kathleen A., Thorsson, Vesteinn, Li, Bin, Gilchrist, Mark, Gold, Elizabeth S., Johnson, Carrie D., Litvak, Vladimir, Navarro, Garnet, Roach, Jared C., Rosenberger, Carrie M., Rust, Alistair G., Yudkovsky, Natalya, Aderem, Alan, Shmulevich, Ilya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265556/
https://www.ncbi.nlm.nih.gov/pubmed/18369420
http://dx.doi.org/10.1371/journal.pcbi.1000021

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