IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis

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Nuclear factor κB (NF-κB) is involved in multiple skeletal muscle disorders, but how it functions in differentiation remains elusive given that both anti- and promyogenic activities have been described. In this study, we resolve this by showing that myogenesis is controlled by opposing NF-κB signali...

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Detalles Bibliográficos
Autores principales: Bakkar, Nadine, Wang, Jingxin, Ladner, Katherine J., Wang, Huating, Dahlman, Jason M., Carathers, Micheal, Acharyya, Swarnali, Rudnicki, Michael A., Hollenbach, Andrew D., Guttridge, Denis C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265568/
https://www.ncbi.nlm.nih.gov/pubmed/18299349
http://dx.doi.org/10.1083/jcb.200707179
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