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The effects of a partitioned var gene repertoire of Plasmodium falciparum on antigenic diversity and the acquisition of clinical immunity
BACKGROUND: The human malaria parasite Plasmodium falciparum exploits antigenic diversity and within-host antigenic variation to evade the host's immune system. Of particular importance are the highly polymorphic var genes that encode the family of cell surface antigens PfEMP1 (Plasmodium falci...
Autores principales: | Recker, Mario, Arinaminpathy, Nimalan, Buckee, Caroline O |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265724/ https://www.ncbi.nlm.nih.gov/pubmed/18215289 http://dx.doi.org/10.1186/1475-2875-7-18 |
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