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Exploring the Developmental Overnutrition Hypothesis Using Parental–Offspring Associations and FTO as an Instrumental Variable

BACKGROUND: The developmental overnutrition hypothesis suggests that greater maternal obesity during pregnancy results in increased offspring adiposity in later life. If true, this would result in the obesity epidemic progressing across generations irrespective of environmental or genetic changes. I...

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Detalles Bibliográficos
Autores principales:	Lawlor, Debbie A, Timpson, Nicholas J, Harbord, Roger M, Leary, Sam, Ness, Andy, McCarthy, Mark I, Frayling, Timothy M, Hattersley, Andrew T, Smith, George Davey
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265763/ https://www.ncbi.nlm.nih.gov/pubmed/18336062 http://dx.doi.org/10.1371/journal.pmed.0050033

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