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The Glutamate Transporter Subtypes EAAT4 and EAATs 1-3 Transport Glutamate with Dramatically Different Kinetics and Voltage Dependence but Share a Common Uptake Mechanism

Here, we report the application of glutamate concentration jumps and voltage jumps to determine the kinetics of rapid reaction steps of excitatory amino acid transporter subtype 4 (EAAT4) with a 100-μs time resolution. EAAT4 was expressed in HEK293 cells, and the electrogenic transport and anion cur...

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Detalles Bibliográficos
Autores principales:	Mim, Carsten, Balani, Poonam, Rauen, Thomas, Grewer, Christof
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266596/ https://www.ncbi.nlm.nih.gov/pubmed/16316976 http://dx.doi.org/10.1085/jgp.200509365

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