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Electrostatics in the Cytoplasmic Pore Produce Intrinsic Inward Rectification in Kir2.1 Channels
Inward rectifier K(+) channels are important in regulating membrane excitability in many cell types. The physiological functions of these channels are related to their unique inward rectification, which has been attributed to voltage-dependent block. Here, we show that inward rectification can also...
Autores principales: | Yeh, Shih-Hao, Chang, Hsueh-Kai, Shieh, Ru-Chi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266598/ https://www.ncbi.nlm.nih.gov/pubmed/16316974 http://dx.doi.org/10.1085/jgp.200509367 |
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