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Heme Regulates Allosteric Activation of the Slo1 BK Channel

Large conductance calcium-dependent (Slo1 BK) channels are allosterically activated by membrane depolarization and divalent cations, and possess a rich modulatory repertoire. Recently, intracellular heme has been identified as a potent regulator of Slo1 BK channels (Tang, X.D., R. Xu, M.F. Reynolds,...

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Detalles Bibliográficos
Autores principales:	Horrigan, Frank T., Heinemann, Stefan H., Hoshi, Toshinori
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266614/ https://www.ncbi.nlm.nih.gov/pubmed/15955873 http://dx.doi.org/10.1085/jgp.200509262

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