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A Ca(V)β SH3/Guanylate Kinase Domain Interaction Regulates Multiple Properties of Voltage-gated Ca(2+) Channels

Auxiliary Ca(2+) channel β subunits (Ca(V)β) regulate cellular Ca(2+) signaling by trafficking pore-forming α(1) subunits to the membrane and normalizing channel gating. These effects are mediated through a characteristic src homology 3/guanylate kinase (SH3–GK) structural module, a design feature s...

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Detalles Bibliográficos
Autores principales:	Takahashi, Shoji X., Miriyala, Jayalakshmi, Tay, Lai Hock, Yue, David T., Colecraft, Henry M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266626/ https://www.ncbi.nlm.nih.gov/pubmed/16186563 http://dx.doi.org/10.1085/jgp.200509354

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