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Differential production of superoxide by neuronal mitochondria

BACKGROUND: Mitochondrial DNA (mtDNA) mutations, which are present in all mitochondria-containing cells, paradoxically cause tissue-specific disease. For example, Leber's hereditary optic neuropathy (LHON) results from one of three point mutations mtDNA coding for complex I components, but is o...

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Detalles Bibliográficos
Autores principales:	Hoegger, Mark J, Lieven, Christopher J, Levin, Leonard A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266764/ https://www.ncbi.nlm.nih.gov/pubmed/18182110 http://dx.doi.org/10.1186/1471-2202-9-4

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