Obesity and HER 2 overexpression: a common factor for poor prognosis of breast cancer

BACKGROUND: Both obesity and over-expression of HER II are associated with poor prognosis of breast cancer. In vitro experiments suggest that anti-tumour activity of the anti-obesity drug Orlistat is likely to be due to transcriptional suppression of HER II expression. The overexpression of HER II i...

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Detalles Bibliográficos
Autores principales: Sellahewa, Chaminda, Nightingale, Peter, Carmichael, Amtul R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266765/
https://www.ncbi.nlm.nih.gov/pubmed/18294401
http://dx.doi.org/10.1186/1477-7800-5-2

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