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Rosiglitazone but not losartan prevents Nrf-2 dependent CD36 gene expression up-regulation in an in vivo atherosclerosis model

BACKGROUND: Thiazolidinediones exert anti-inflammatory and anti-oxidative roles and attenuate atherosclerosis by mechanisms partially independent of their metabolizing actions. High doses of angiotensin type 1 receptor (AT(1)R) blocker losartan (LST) seem to promote fat cell formation by preserving...

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Detalles Bibliográficos
Autores principales:	Hernandez-Trujillo, Y, Rodriguez-Esparragon, F, Macias-Reyes, A, Caballero-Hidalgo, A, Rodriguez-Perez, Jose C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266907/ https://www.ncbi.nlm.nih.gov/pubmed/18302760 http://dx.doi.org/10.1186/1475-2840-7-3

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