Evolution of a family of metazoan active-site-serine enzymes from penicillin-binding proteins: a novel facet of the bacterial legacy

BACKGROUND: Bacterial penicillin-binding proteins and β-lactamases (PBP-βLs) constitute a large family of serine proteases that perform essential functions in the synthesis and maintenance of peptidoglycan. Intriguingly, genes encoding PBP-βL homologs occur in many metazoan genomes including humans....

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Detalles Bibliográficos
Autores principales: Peitsaro, Nina, Polianskyte, Zydrune, Tuimala, Jarno, Pörn-Ares, Isabella, Liobikas, Julius, Speer, Oliver, Lindholm, Dan, Thompson, James, Eriksson, Ove
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266909/
https://www.ncbi.nlm.nih.gov/pubmed/18226203
http://dx.doi.org/10.1186/1471-2148-8-26

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