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Socio-economic class, rurality and risk of cutaneous melanoma by site and gender in Sweden

BACKGROUND: Cutaneous melanoma (CM) is a cancer usually associated with high socio-economic level in the literature. Few studies have, however, assessed this relationship by gender and site or the association between CM and rurality. METHODS: A major-sized historical occupational Swedish cohort comp...

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Autores principales: Pérez-Gómez, Beatriz, Aragonés, Nuria, Gustavsson, Per, Lope, Virginia, López-Abente, Gonzalo, Pollán, Marina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266924/
https://www.ncbi.nlm.nih.gov/pubmed/18221505
http://dx.doi.org/10.1186/1471-2458-8-33
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author Pérez-Gómez, Beatriz
Aragonés, Nuria
Gustavsson, Per
Lope, Virginia
López-Abente, Gonzalo
Pollán, Marina
author_facet Pérez-Gómez, Beatriz
Aragonés, Nuria
Gustavsson, Per
Lope, Virginia
López-Abente, Gonzalo
Pollán, Marina
author_sort Pérez-Gómez, Beatriz
collection PubMed
description BACKGROUND: Cutaneous melanoma (CM) is a cancer usually associated with high socio-economic level in the literature. Few studies have, however, assessed this relationship by gender and site or the association between CM and rurality. METHODS: A major-sized historical occupational Swedish cohort comprising 2,992,166 workers was used to estimate relative risk of cutaneous melanoma, broken down by gender and anatomical site, for occupational sectors (as a proxy of socio-economic class) and rurality. To this end, Poisson models were fitted for each site in men and women, including occupational sector and town size, with adjustment for age, period of diagnosis and geographical area as possible confounding factors. RESULTS: White collar workers presented a marked increased of risk in men in all melanoma cases, as well as in trunk, upper and lower limbs. This pattern was less clear for women, in which some heterogeneity appeared, as low risks in lower socioeconomic sectors in trunk, or risk excesses in white collar workers in lower limbs did not achieve statistical significance. Males also showed significant differences in risk by rural/urban distribution, but in women this association was limited to CM of lower limb. Risk of CM of head/neck did not vary by occupational sector or town size, thus depicting a specific epidemiological profile, which proved common to both sexes. CONCLUSION: While differences in risk between men and women could suggest greater homogeneity in UV-exposure behaviour among women, the uniform risk pattern in head and neck melanoma, present in both sexes, might support the coexistence of different aetiological pathways, related to anatomical site.
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spelling pubmed-22669242008-03-12 Socio-economic class, rurality and risk of cutaneous melanoma by site and gender in Sweden Pérez-Gómez, Beatriz Aragonés, Nuria Gustavsson, Per Lope, Virginia López-Abente, Gonzalo Pollán, Marina BMC Public Health Research Article BACKGROUND: Cutaneous melanoma (CM) is a cancer usually associated with high socio-economic level in the literature. Few studies have, however, assessed this relationship by gender and site or the association between CM and rurality. METHODS: A major-sized historical occupational Swedish cohort comprising 2,992,166 workers was used to estimate relative risk of cutaneous melanoma, broken down by gender and anatomical site, for occupational sectors (as a proxy of socio-economic class) and rurality. To this end, Poisson models were fitted for each site in men and women, including occupational sector and town size, with adjustment for age, period of diagnosis and geographical area as possible confounding factors. RESULTS: White collar workers presented a marked increased of risk in men in all melanoma cases, as well as in trunk, upper and lower limbs. This pattern was less clear for women, in which some heterogeneity appeared, as low risks in lower socioeconomic sectors in trunk, or risk excesses in white collar workers in lower limbs did not achieve statistical significance. Males also showed significant differences in risk by rural/urban distribution, but in women this association was limited to CM of lower limb. Risk of CM of head/neck did not vary by occupational sector or town size, thus depicting a specific epidemiological profile, which proved common to both sexes. CONCLUSION: While differences in risk between men and women could suggest greater homogeneity in UV-exposure behaviour among women, the uniform risk pattern in head and neck melanoma, present in both sexes, might support the coexistence of different aetiological pathways, related to anatomical site. BioMed Central 2008-01-25 /pmc/articles/PMC2266924/ /pubmed/18221505 http://dx.doi.org/10.1186/1471-2458-8-33 Text en Copyright © 2008 Pérez-Gómez et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Pérez-Gómez, Beatriz
Aragonés, Nuria
Gustavsson, Per
Lope, Virginia
López-Abente, Gonzalo
Pollán, Marina
Socio-economic class, rurality and risk of cutaneous melanoma by site and gender in Sweden
title Socio-economic class, rurality and risk of cutaneous melanoma by site and gender in Sweden
title_full Socio-economic class, rurality and risk of cutaneous melanoma by site and gender in Sweden
title_fullStr Socio-economic class, rurality and risk of cutaneous melanoma by site and gender in Sweden
title_full_unstemmed Socio-economic class, rurality and risk of cutaneous melanoma by site and gender in Sweden
title_short Socio-economic class, rurality and risk of cutaneous melanoma by site and gender in Sweden
title_sort socio-economic class, rurality and risk of cutaneous melanoma by site and gender in sweden
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266924/
https://www.ncbi.nlm.nih.gov/pubmed/18221505
http://dx.doi.org/10.1186/1471-2458-8-33
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