Simultaneous targeted exchange of two nucleotides by single-stranded oligonucleotides clusters within a region of about fourteen nucleotides

BACKGROUND: Transfection of cells with gene-specific, single-stranded oligonucleotides can induce the targeted exchange of one or two nucleotides in the targeted gene. To characterize the features of the DNA-repair mechanisms involved, we examined the maximal distance for the simultaneous exchange o...

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Detalles Bibliográficos
Autores principales: Hegele, Heike, Wuepping, Matthias, Ref, Caroline, Kenner, Oliver, Kaufmann, Dieter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266939/
https://www.ncbi.nlm.nih.gov/pubmed/18226192
http://dx.doi.org/10.1186/1471-2199-9-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266939/
https://www.ncbi.nlm.nih.gov/pubmed/18226192
http://dx.doi.org/10.1186/1471-2199-9-14

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