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Oxidative Activity of Copper(II) Complexes with Aminoglycoside Antibiotics as Implication to the Toxicity of These Drugs

The majority of aminoglycosidic antibiotics anchor Cu(ll) ions by {NH(2), O} chelates of the A and C rings of its molecule as distinct from amikacin, which belongs to the class of substituted ones. The results indicate that all these antibiotics effectively bind copper(ll) at physiological pH. Cycli...

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Detalles Bibliográficos
Autores principales: Szczepanik, Wojciech, Kaczmarek, Piotr, Jeżowska-Bojczuk, Małgorzata
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267070/
https://www.ncbi.nlm.nih.gov/pubmed/18365069
http://dx.doi.org/10.1155/S1565363304000056