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Oxidative Activity of Copper(II) Complexes with Aminoglycoside Antibiotics as Implication to the Toxicity of These Drugs
The majority of aminoglycosidic antibiotics anchor Cu(ll) ions by {NH(2), O} chelates of the A and C rings of its molecule as distinct from amikacin, which belongs to the class of substituted ones. The results indicate that all these antibiotics effectively bind copper(ll) at physiological pH. Cycli...
Autores principales: | Szczepanik, Wojciech, Kaczmarek, Piotr, Jeżowska-Bojczuk, Małgorzata |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267070/ https://www.ncbi.nlm.nih.gov/pubmed/18365069 http://dx.doi.org/10.1155/S1565363304000056 |
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