DNA Interactions with Ruthenium(ll) Polypyridine Complexes Containing Asymmetric Ligands

In an attempt to probe nucleic acid structures, numerous Ru(II) complexes with different ligands have been synthesized and investigated. In this contribution we focus on the DNA-binding properties of ruthenium(II) complexes containing asymmetric ligands that have attracted little attention in the pa...

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Detalles Bibliográficos
Autores principales: Chao, Hui, Ji, Liang-Nian
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267087/
https://www.ncbi.nlm.nih.gov/pubmed/18365086
http://dx.doi.org/10.1155/BCA.2005.15
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author Chao, Hui
Ji, Liang-Nian
author_facet Chao, Hui
Ji, Liang-Nian
author_sort Chao, Hui
collection PubMed
description In an attempt to probe nucleic acid structures, numerous Ru(II) complexes with different ligands have been synthesized and investigated. In this contribution we focus on the DNA-binding properties of ruthenium(II) complexes containing asymmetric ligands that have attracted little attention in the past decades. The influences of the shape and size of the ligand on the binding modes, affinity, enantioselectivities and photocleavage of the complexes to DNA are described.
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spelling pubmed-22670872008-03-24 DNA Interactions with Ruthenium(ll) Polypyridine Complexes Containing Asymmetric Ligands Chao, Hui Ji, Liang-Nian Bioinorg Chem Appl Research Article In an attempt to probe nucleic acid structures, numerous Ru(II) complexes with different ligands have been synthesized and investigated. In this contribution we focus on the DNA-binding properties of ruthenium(II) complexes containing asymmetric ligands that have attracted little attention in the past decades. The influences of the shape and size of the ligand on the binding modes, affinity, enantioselectivities and photocleavage of the complexes to DNA are described. Hindawi Publishing Corporation 2005 /pmc/articles/PMC2267087/ /pubmed/18365086 http://dx.doi.org/10.1155/BCA.2005.15 Text en Copyright © 2005 Hui Chao and Liang-Nian Ji. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Chao, Hui
Ji, Liang-Nian
DNA Interactions with Ruthenium(ll) Polypyridine Complexes Containing Asymmetric Ligands
title DNA Interactions with Ruthenium(ll) Polypyridine Complexes Containing Asymmetric Ligands
title_full DNA Interactions with Ruthenium(ll) Polypyridine Complexes Containing Asymmetric Ligands
title_fullStr DNA Interactions with Ruthenium(ll) Polypyridine Complexes Containing Asymmetric Ligands
title_full_unstemmed DNA Interactions with Ruthenium(ll) Polypyridine Complexes Containing Asymmetric Ligands
title_short DNA Interactions with Ruthenium(ll) Polypyridine Complexes Containing Asymmetric Ligands
title_sort dna interactions with ruthenium(ll) polypyridine complexes containing asymmetric ligands
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267087/
https://www.ncbi.nlm.nih.gov/pubmed/18365086
http://dx.doi.org/10.1155/BCA.2005.15
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