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Probing Intranuclear Environments at the Single-Molecule Level

Genome activity and nuclear metabolism clearly depend on accessibility, but it is not known whether and to what extent nuclear structures limit the mobility and access of individual molecules. We used fluorescently labeled streptavidin with a nuclear localization signal as an average-sized, inert pr...

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Detalles Bibliográficos
Autores principales: Grünwald, David, Martin, Robert M., Buschmann, Volker, Bazett-Jones, David P., Leonhardt, Heinrich, Kubitscheck, Ulrich, Cardoso, M. Cristina
Formato: Texto
Lenguaje:English
Publicado: The Biophysical Society 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267134/
https://www.ncbi.nlm.nih.gov/pubmed/18065482
http://dx.doi.org/10.1529/biophysj.107.115014