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Probing Intranuclear Environments at the Single-Molecule Level
Genome activity and nuclear metabolism clearly depend on accessibility, but it is not known whether and to what extent nuclear structures limit the mobility and access of individual molecules. We used fluorescently labeled streptavidin with a nuclear localization signal as an average-sized, inert pr...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267134/ https://www.ncbi.nlm.nih.gov/pubmed/18065482 http://dx.doi.org/10.1529/biophysj.107.115014 |