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A Dual-Color Fluorescence-Based Platform to Identify Selective Inhibitors of Akt Signaling
BACKGROUND: Inhibition of Akt signaling is considered one of the most promising therapeutic strategies for many cancers. However, rational target-orientated approaches to cell based drug screens for anti-cancer agents have historically been compromised by the notorious absence of suitable control ce...
Autores principales: | Rosado, Aranzazú, Zanella, Fabian, Garcia, Beatriz, Carnero, Amancio, Link, Wolfgang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267216/ https://www.ncbi.nlm.nih.gov/pubmed/18350159 http://dx.doi.org/10.1371/journal.pone.0001823 |
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