Aggressive immunosuppressive treatment of Susac's syndrome in an adolescent: using treatment of dermatomyositis as a model

We describe aggressive immunosuppressive treatment of an adolescent with Susac's syndrome (SS), a disease of the microvasculature in the brain, retina, and inner ear. Because the immunopathogenesis of SS appears to have much in common with that of juvenile dermatomyositis (JDM), the patient was...

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Autores principales: Rennebohm, Robert M, Lubow, Martin, Rusin, Jerome, Martin, Lisa, Grzybowski, Deborah M, Susac, John O
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267466/
https://www.ncbi.nlm.nih.gov/pubmed/18230188
http://dx.doi.org/10.1186/1546-0096-6-3
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author Rennebohm, Robert M
Lubow, Martin
Rusin, Jerome
Martin, Lisa
Grzybowski, Deborah M
Susac, John O
author_facet Rennebohm, Robert M
Lubow, Martin
Rusin, Jerome
Martin, Lisa
Grzybowski, Deborah M
Susac, John O
author_sort Rennebohm, Robert M
collection PubMed
description We describe aggressive immunosuppressive treatment of an adolescent with Susac's syndrome (SS), a disease of the microvasculature in the brain, retina, and inner ear. Because the immunopathogenesis of SS appears to have much in common with that of juvenile dermatomyositis (JDM), the patient was treated with an approach that has been effective for severe JDM. The patient's outcome provides evidence for the importance of prompt, aggressive, and sustained immunosuppressive treatment of encephalopathic SS.
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spelling pubmed-22674662008-03-14 Aggressive immunosuppressive treatment of Susac's syndrome in an adolescent: using treatment of dermatomyositis as a model Rennebohm, Robert M Lubow, Martin Rusin, Jerome Martin, Lisa Grzybowski, Deborah M Susac, John O Pediatr Rheumatol Online J Case Report We describe aggressive immunosuppressive treatment of an adolescent with Susac's syndrome (SS), a disease of the microvasculature in the brain, retina, and inner ear. Because the immunopathogenesis of SS appears to have much in common with that of juvenile dermatomyositis (JDM), the patient was treated with an approach that has been effective for severe JDM. The patient's outcome provides evidence for the importance of prompt, aggressive, and sustained immunosuppressive treatment of encephalopathic SS. BioMed Central 2008-01-29 /pmc/articles/PMC2267466/ /pubmed/18230188 http://dx.doi.org/10.1186/1546-0096-6-3 Text en Copyright © 2008 Rennebohm et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Rennebohm, Robert M
Lubow, Martin
Rusin, Jerome
Martin, Lisa
Grzybowski, Deborah M
Susac, John O
Aggressive immunosuppressive treatment of Susac's syndrome in an adolescent: using treatment of dermatomyositis as a model
title Aggressive immunosuppressive treatment of Susac's syndrome in an adolescent: using treatment of dermatomyositis as a model
title_full Aggressive immunosuppressive treatment of Susac's syndrome in an adolescent: using treatment of dermatomyositis as a model
title_fullStr Aggressive immunosuppressive treatment of Susac's syndrome in an adolescent: using treatment of dermatomyositis as a model
title_full_unstemmed Aggressive immunosuppressive treatment of Susac's syndrome in an adolescent: using treatment of dermatomyositis as a model
title_short Aggressive immunosuppressive treatment of Susac's syndrome in an adolescent: using treatment of dermatomyositis as a model
title_sort aggressive immunosuppressive treatment of susac's syndrome in an adolescent: using treatment of dermatomyositis as a model
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267466/
https://www.ncbi.nlm.nih.gov/pubmed/18230188
http://dx.doi.org/10.1186/1546-0096-6-3
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