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Association between the PPP3CC gene, coding for the calcineurin gamma catalytic subunit, and bipolar disorder
BACKGROUND: Calcineurin is a neuron-enriched phosphatase that regulates synaptic plasticity and neuronal adaptation. Activation of calcineurin, overall, antagonizes the effects of the cyclic AMP activated protein/kinase A. Thus, kinase/phosphatase dynamic balance seems to be critical for transition...
Autores principales: | Mathieu, Flavie, Miot, Stéphanie, Etain, Bruno, El Khoury, Marie-Anne, Chevalier, Fabien, Bellivier, Frank, Leboyer, Marion, Giros, Bruno, Tzavara, Eleni T |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267477/ https://www.ncbi.nlm.nih.gov/pubmed/18201382 http://dx.doi.org/10.1186/1744-9081-4-2 |
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