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The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction

BACKGROUND: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are tolerated. The rise in available protein sequences continues to increase the power of techniques based on this principle....

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Detalles Bibliográficos
Autores principales: Manning, Jonathan R, Jefferson, Emily R, Barton, Geoffrey J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267696/
https://www.ncbi.nlm.nih.gov/pubmed/18221517
http://dx.doi.org/10.1186/1471-2105-9-51

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