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The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
BACKGROUND: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are tolerated. The rise in available protein sequences continues to increase the power of techniques based on this principle....
Autores principales: | Manning, Jonathan R, Jefferson, Emily R, Barton, Geoffrey J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267696/ https://www.ncbi.nlm.nih.gov/pubmed/18221517 http://dx.doi.org/10.1186/1471-2105-9-51 |
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