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Predicting synthetic rescues in metabolic networks

An important goal of medical research is to develop methods to recover the loss of cellular function due to mutations and other defects. Many approaches based on gene therapy aim to repair the defective gene or to insert genes with compensatory function. Here, we propose an alternative, network-base...

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Detalles Bibliográficos
Autores principales: Motter, Adilson E, Gulbahce, Natali, Almaas, Eivind, Barabási, Albert-László
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267730/
https://www.ncbi.nlm.nih.gov/pubmed/18277384
http://dx.doi.org/10.1038/msb.2008.1

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