Cargando…

Components of the ubiquitin-proteasome pathway compete for surfaces on Rad23 family proteins

BACKGROUND: The delivery of ubiquitinated proteins to the proteasome for degradation is a key step in the regulation of the ubiquitin-proteasome pathway, yet the mechanisms underlying this step are not understood in detail. The Rad23 family of proteins is known to bind ubiquitinated proteins through...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goh, Amanda M, Walters, Kylie J, Elsasser, Suzanne, Verma, Rati, Deshaies, Raymond J, Finley, Daniel, Howley, Peter M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267792/ https://www.ncbi.nlm.nih.gov/pubmed/18234089 http://dx.doi.org/10.1186/1471-2091-9-4

Ejemplares similares

Proteotoxic crisis, the ubiquitin-proteasome system, and cancer therapy
por: Deshaies, Raymond J
Publicado: (2014)

Rad23 escapes degradation because it lacks a proteasome initiation region
por: Fishbain, Susan, et al.
Publicado: (2011)

NEDD8 links Cullin–Ring ubiquitin Ligase function to the p97 pathway
por: den Besten, Willem, et al.
Publicado: (2012)

Ribosomal proteins produced in excess are degraded by the ubiquitin–proteasome system
por: Sung, Min-Kyung, et al.
Publicado: (2016)

Quantitative Cell-based Protein Degradation Assays to Identify and Classify Drugs That Target the Ubiquitin-Proteasome System
por: Chou, Tsui-Fen, et al.
Publicado: (2011)

Ubiquitin-Binding Site 2 of ataxin-3 prevents its proteasomal degradation by interacting with Rad23
por: Blount, Jessica R., et al.
Publicado: (2014)

USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites
por: Lee, Byung-Hoon, et al.
Publicado: (2016)

The proteasome 19S cap and its ubiquitin receptors provide a versatile recognition platform for substrates
por: Martinez-Fonts, Kirby, et al.
Publicado: (2020)

Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome
por: Verma, Rati, et al.
Publicado: (2013)

UV induced ubiquitination of the yeast Rad4–Rad23 complex promotes survival by regulating cellular dNTP pools
por: Zhou, Zheng, et al.
Publicado: (2015)

(1)H, (15)N, (13)C resonance assignments for proteasome shuttle factor hHR23a
por: Chen, Xiang, et al.
Publicado: (2023)

N-Terminal Ubiquitination of Amyloidogenic Proteins Triggers Removal of Their Oligomers by the Proteasome Holoenzyme
por: Ye, Yu, et al.
Publicado: (2020)

Lysine deserts prevent adventitious ubiquitylation of ubiquitin-proteasome components
por: Kampmeyer, Caroline, et al.
Publicado: (2023)

JAMM: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome
por: Ambroggio, Xavier I, et al.
Publicado: (2004)

Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system
por: Xu, Daichao, et al.
Publicado: (2015)

The ubiquitin-proteasome pathway in cancer.
por: Spataro, V., et al.
Publicado: (1998)

The ubiquitin proteasome system in neuropathology
por: Lehman, Norman L.
Publicado: (2009)

The recognition of ubiquitinated proteins by the proteasome
por: Grice, Guinevere L., et al.
Publicado: (2016)

The Acidic Tail of the Cdc34 Ubiquitin-conjugating Enzyme Functions in Both Binding to and Catalysis with Ubiquitin Ligase SCF(Cdc4)
por: Kleiger, Gary, et al.
Publicado: (2009)

Measuring ubiquitin chain linkage: Rap80 uses a molecular ruler mechanism for ubiquitin linkage specificity
por: Walters, Kylie J, et al.
Publicado: (2009)

Identification of ubiquitin-proteasome system components affecting the degradation of the transcription factor Pap1
por: Marte, Luis, et al.
Publicado: (2019)

Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation
por: Choi, Won Hoon, et al.
Publicado: (2016)

The Ubiquitin Proteasome System in Genome Stability and Cancer
por: Morgan, Jonathan J., et al.
Publicado: (2021)

p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition
por: Radhakrishnan, Senthil K, et al.
Publicado: (2014)

Structural Organization of the 19S Proteasome Lid: Insights from MS of Intact Complexes
por: Sharon, Michal, et al.
Publicado: (2006)

Ubiquitin–proteasome system involvement in Huntington’s disease
por: Ortega, Zaira, et al.
Publicado: (2014)

The Ubiquitin Conjugating Enzyme: An Important Ubiquitin Transfer Platform in Ubiquitin-Proteasome System
por: Liu, Weigang, et al.
Publicado: (2020)

Arabidopsis CIPK26 interacts with KEG, components of the ABA signalling network and is degraded by the ubiquitin–proteasome system
por: Lyzenga, Wendy J., et al.
Publicado: (2013)

Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration
por: Lobanova, Ekaterina S., et al.
Publicado: (2018)

Poxvirus Exploitation of the Ubiquitin-Proteasome System
por: Barry, Michele, et al.
Publicado: (2010)

The Ubiquitin-Proteasome Pathway in Huntington's Disease
por: Mitra, Siddhartha, et al.
Publicado: (2008)

Enzymatic Blockade of the Ubiquitin-Proteasome Pathway
por: Ernst, Robert, et al.
Publicado: (2011)

The ubiquitin-proteasome system in Alzheimer's disease
por: Oddo, Salvatore
Publicado: (2008)

Autoregulation of the 26S proteasome by in situ ubiquitination
por: Jacobson, Andrew D., et al.
Publicado: (2014)

Ubiquitin Proteasome System in Stress and Disease
por: Karpov, Dmitry, et al.
Publicado: (2012)

Intracellular Dynamics of the Ubiquitin-Proteasome-System
por: Chowdhury, Maisha, et al.
Publicado: (2015)

Ubiquitin-Proteasome System in Neurodegenerative Disorders
por: Rao, Geeta, et al.
Publicado: (2015)

The Ubiquitin–Proteasome System in Immune Cells
por: Çetin, Gonca, et al.
Publicado: (2021)

Ubiquitin-proteasome system in diabetic retinopathy
por: Svikle, Zane, et al.
Publicado: (2022)

Copper homeostasis and the ubiquitin proteasome system
por: Zhang, Bichao, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_dc612f1t21262cjvljuh1atufo