HIV-1 infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages

BACKGROUND: Macrophages are important targets and long-lived reservoirs of HIV-1, which are not cleared of infection by currently available treatments. In the primary monocyte-derived macrophage model of infection, replication is initially productive followed by a decline in virion output over ensui...

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Detalles Bibliográficos
Autores principales: Dowling, Dinushka, Nasr-Esfahani, Somayeh, Tan, Chun H, O'Brien, Kate, Howard, Jane L, Jans, David A, Purcell, Damian FJ, Stoltzfus, C Martin, Sonza, Secondo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267807/
https://www.ncbi.nlm.nih.gov/pubmed/18241354
http://dx.doi.org/10.1186/1742-4690-5-18

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