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Background frequencies for residue variability estimates: BLOSUM revisited
BACKGROUND: Shannon entropy applied to columns of multiple sequence alignments as a score of residue conservation has proven one of the most fruitful ideas in bioinformatics. This straightforward and intuitively appealing measure clearly shows the regions of a protein under increased evolutionary pr...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267808/ https://www.ncbi.nlm.nih.gov/pubmed/18162129 http://dx.doi.org/10.1186/1471-2105-8-488 |