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Increased Microerythrocyte Count in Homozygous α(+)-Thalassaemia Contributes to Protection against Severe Malarial Anaemia

BACKGROUND: The heritable haemoglobinopathy α(+)-thalassaemia is caused by the reduced synthesis of α-globin chains that form part of normal adult haemoglobin (Hb). Individuals homozygous for α(+)-thalassaemia have microcytosis and an increased erythrocyte count. α(+)-Thalassaemia homozygosity confe...

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Detalles Bibliográficos
Autores principales:	Fowkes, Freya J. I, Allen, Stephen J, Allen, Angela, Alpers, Michael P, Weatherall, David J, Day, Karen P
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267813/ https://www.ncbi.nlm.nih.gov/pubmed/18351796 http://dx.doi.org/10.1371/journal.pmed.0050056

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