Cargando…

Site-directed mutagenesis of Arginine282 suggests how protons and peptides are co-transported by rabbit PepT1

The mammalian proton-coupled peptide transporter PepT1 is the major route of uptake for dietary nitrogen, as well as the oral absorption of a number of drugs, including β-lactam antibiotics and angiotensin-converting enzyme inhibitors. Here we have used site-directed mutagenesis to investigate furth...

Descripción completa

Detalles Bibliográficos
Autores principales: Pieri, Myrtani, Hall, Dashiell, Price, Richard, Bailey, Patrick, Meredith, David
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267855/
https://www.ncbi.nlm.nih.gov/pubmed/18037334
http://dx.doi.org/10.1016/j.biocel.2007.10.010