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Site-directed mutagenesis of Arginine282 suggests how protons and peptides are co-transported by rabbit PepT1
The mammalian proton-coupled peptide transporter PepT1 is the major route of uptake for dietary nitrogen, as well as the oral absorption of a number of drugs, including β-lactam antibiotics and angiotensin-converting enzyme inhibitors. Here we have used site-directed mutagenesis to investigate furth...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267855/ https://www.ncbi.nlm.nih.gov/pubmed/18037334 http://dx.doi.org/10.1016/j.biocel.2007.10.010 |