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Distinct Methylation Changes at the IGF2-H19 Locus in Congenital Growth Disorders and Cancer

BACKGROUND: Differentially methylated regions (DMRs) are associated with many imprinted genes. In mice methylation at a DMR upstream of the H19 gene known as the Imprint Control region (IC1) is acquired in the male germline and influences the methylation status of DMRs 100 kb away in the adjacent In...

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Detalles Bibliográficos
Autores principales:	Murrell, Adele, Ito, Yoko, Verde, Gaetano, Huddleston, Joanna, Woodfine, Kathryn, Silengo, Margherita Cirillo, Spreafico, Filippo, Perotti, Daniela, De Crescenzo, Agostina, Sparago, Angela, Cerrato, Flavia, Riccio, Andrea
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268001/ https://www.ncbi.nlm.nih.gov/pubmed/18365005 http://dx.doi.org/10.1371/journal.pone.0001849

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