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Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly

Persistent infection with the hepatitis C virus (HCV) is a major risk factor for the development of liver cirrhosis and hepatocellular carcinoma. With an estimated about 3% of the world population infected with this virus, the lack of a prophylactic vaccine and a selective therapy, chronic hepatitis...

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Detalles Bibliográficos
Autores principales: Appel, Nicole, Zayas, Margarita, Miller, Sven, Krijnse-Locker, Jacomine, Schaller, Torsten, Friebe, Peter, Kallis, Stephanie, Engel, Ulrike, Bartenschlager, Ralf
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268006/
https://www.ncbi.nlm.nih.gov/pubmed/18369481
http://dx.doi.org/10.1371/journal.ppat.1000035