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The Efficacy of Tetracyclines in Peripheral and Intracerebral Prion Infection
We have previously shown that tetracyclines interact with and reverse the protease resistance of pathological prion protein extracted from scrapie-infected animals and patients with all forms of Creutzfeldt-Jakob disease, lowering the prion titre and prolonging survival of cerebrally infected animal...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268013/ https://www.ncbi.nlm.nih.gov/pubmed/18365024 http://dx.doi.org/10.1371/journal.pone.0001888 |