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Entropy Measures Quantify Global Splicing Disorders in Cancer
Most mammalian genes are able to express several splice variants in a phenomenon known as alternative splicing. Serious alterations of alternative splicing occur in cancer tissues, leading to expression of multiple aberrant splice forms. Most studies of alternative splicing defects have focused on t...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268240/ https://www.ncbi.nlm.nih.gov/pubmed/18369415 http://dx.doi.org/10.1371/journal.pcbi.1000011 |