The atypical mammalian ligand Delta-like homologue 1 (Dlk1) can regulate Notch signalling in Drosophila

BACKGROUND: Mammalian Delta-like 1 (Dlk-1) protein shares homology with Notch ligands but lacks a critical receptor-binding domain. Thus it is unclear whether it is able to interact with Notch in vivo. Unlike mammals, Drosophila have a single Notch receptor allowing a simple in vivo assay for mammal...

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Detalles Bibliográficos
Autores principales: Bray, Sarah J, Takada, Shuji, Harrison, Emma, Shen, Shing-Chuan, Ferguson-Smith, Anne C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268666/
https://www.ncbi.nlm.nih.gov/pubmed/18237417
http://dx.doi.org/10.1186/1471-213X-8-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268666/
https://www.ncbi.nlm.nih.gov/pubmed/18237417
http://dx.doi.org/10.1186/1471-213X-8-11

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