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Alterations in the Notch4 pathway in cerebral endothelial cells by the HIV aspartyl protease inhibitor, nelfinavir

BACKGROUND: Aspartyl protease inhibitors (PIs) used to treat HIV belong to an important group of drugs that influence significantly endothelial cell functioning and angiogenic capacity, although specific mechanisms are poorly understood. Recently, PIs, particularly Nelfinavir, were reported to disru...

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Detalles Bibliográficos
Autores principales:	Grigorian, Aline, Hurford, Rosemary, Chao, Ying, Patrick, Christina, Langford, T Dianne
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268698/ https://www.ncbi.nlm.nih.gov/pubmed/18302767 http://dx.doi.org/10.1186/1471-2202-9-27

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