Robust hypoxia-selective regulation of a retinal pigment epithelium-specific adeno-associated virus vector

PURPOSE: To develop an hypoxia-regulated retinal pigment epithelium (RPE)-specific adeno-associated virus (AAV) gene transfer platform that exploits hypoxia as a physiologic trigger for an early antiangiogenic treatment strategy directed at arresting neovascularization in the eye. METHODS: Tissue-sp...

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Detalles Bibliográficos
Autores principales: Dougherty, Christopher J., Smith, George W., Dorey, C. Kathleen, Prentice, Howard M., Webster, Keith A., Blanks, Janet C.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268848/
https://www.ncbi.nlm.nih.gov/pubmed/18334957

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