Expression of K6W-ubiquitin in lens epithelial cells leads to upregulation of a broad spectrum of molecular chaperones

PURPOSE: Accumulation and precipitation of abnormal proteins are associated with many age-related diseases. The ubiquitin-proteasome pathway (UPP) is one of the protein quality control mechanisms that selectively degrade damaged or obsolete proteins. The other arm of the protein quality control mech...

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Detalles Bibliográficos
Autores principales: Bian, Q, Fernandes, AF, Taylor, A, Wu, M, Pereira, P, Shang, F
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268857/
https://www.ncbi.nlm.nih.gov/pubmed/18334961

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