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Cell Death by SecTRAPs: Thioredoxin Reductase as a Prooxidant Killer of Cells

BACKGROUND: SecTRAPs (selenium compromised thioredoxin reductase-derived apoptotic proteins) can be formed from the selenoprotein thioredoxin reductase (TrxR) by targeting of its selenocysteine (Sec) residue with electrophiles, or by its removal through C-terminal truncation. SecTRAPs are devoid of...

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Detalles Bibliográficos
Autores principales: Anestål, Karin, Prast-Nielsen, Stefanie, Cenas, Narimantas, Arnér, Elias S. J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268967/
https://www.ncbi.nlm.nih.gov/pubmed/18382651
http://dx.doi.org/10.1371/journal.pone.0001846