Cargando…
Pharmacological separation of early afterdepolarizations from arrhythmogenic substrate in ΔKPQ Scn5a murine hearts modelling human long QT 3 syndrome
AIM: To perform an empirical, pharmacological, separation of early afterdepolarizations (EADs) and transmural gradients of repolarization in arrhythmogenesis in a genetically modified mouse heart modelling human long QT syndrome (LQT) 3. METHODS: Left ventricular endocardial and epicardial monophasi...
Autores principales: | Thomas, G, Killeen, M J, Grace, A A, Huang, C L-H |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268972/ https://www.ncbi.nlm.nih.gov/pubmed/17973950 http://dx.doi.org/10.1111/j.1748-1716.2007.01770.x |
Ejemplares similares
-
Atrial arrhythmogenicity in aged Scn5a+/∆KPQ mice modeling long QT type 3 syndrome and its relationship to Na(+) channel expression and cardiac conduction
por: Guzadhur, Laila, et al.
Publicado: (2010) -
Separation of early afterdepolarizations from arrhythmogenic substrate in the isolated perfused hypokalaemic murine heart through modifiers of calcium homeostasis
por: Killeen, M J, et al.
Publicado: (2007) -
Altered sinoatrial node function and intra-atrial conduction in murine gain-of-function Scn5a+/ΔKPQ hearts suggest an overlap syndrome
por: Wu, Jingjing, et al.
Publicado: (2012) -
Cardiomyocyte Deletion of Bmal1 Exacerbates QT- and RR-Interval Prolongation in Scn5a(+/ΔKPQ) Mice
por: Schroder, Elizabeth A., et al.
Publicado: (2021) -
Arrhythmogenic mechanisms in the isolated perfused hypokalaemic murine heart
por: Killeen, M J, et al.
Publicado: (2007)