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Thermal dependency of RAG1 self-association properties

BACKGROUND: Functional immunoglobulin and T cell receptor genes are produced in developing lymphocytes by V(D)J recombination. The initial site-specific DNA cleavage steps in this process are catalyzed by the V(D)J recombinase, consisting of RAG1 and RAG2, which is directed to appropriate DNA cleava...

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Detalles Bibliográficos
Autores principales: De, Pallabi, Zhao, Shuying, Gwyn, Lori M, Godderz, LeAnn J, Peak, Mandy M, Rodgers, Karla K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270275/
https://www.ncbi.nlm.nih.gov/pubmed/18234093
http://dx.doi.org/10.1186/1471-2091-9-5