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Successful adjuvant-free vaccination of BALB/c mice with mutated amyloid β peptides

BACKGROUND: A recent human clinical trial of an Alzheimer's disease (AD) vaccine using amyloid beta (Aβ) 1–42 plus QS-21 adjuvant produced some positive results, but was halted due to meningoencephalitis in some participants. The development of a vaccine with mutant Aβ peptides that avoids the...

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Detalles Bibliográficos
Autores principales:	Cao, Chuanhai, Lin, Xiaoyang, Wahi, Monika M, Jackson, Eugene A, Potter, Huntington
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270279/ https://www.ncbi.nlm.nih.gov/pubmed/18282292 http://dx.doi.org/10.1186/1471-2202-9-25

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