Apoptosis Regulators Fas and Bim Cooperate in Shutdown of Chronic Immune Responses and Prevention of Autoimmunity

Apoptotic death of T lymphocytes is critical for shutdown of immune responses and hemopoietic cell homeostasis. Both death receptor (Fas) activation and mitochondrial apoptosis triggered by the BH3-only protein Bim have been implicated in the killing of antigen-stimulated T cells. We examined mice l...

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Detalles Bibliográficos
Autores principales: Hughes, Peter D., Belz, Gabrielle T., Fortner, Karen A., Budd, Ralph C., Strasser, Andreas, Bouillet, Philippe
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270348/
https://www.ncbi.nlm.nih.gov/pubmed/18275830
http://dx.doi.org/10.1016/j.immuni.2007.12.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270348/
https://www.ncbi.nlm.nih.gov/pubmed/18275830
http://dx.doi.org/10.1016/j.immuni.2007.12.017

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